BGC > Product Search > I-BET762 carboxylic acid | 1300019-38-8

Description :
I-BET762 carboxylic acid is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC50 of 5.1.

• Molecular Weight :396.83

Molecular Formula :
C20H17ClN4O3
Canonical SMILES :
CC1=NN=C2N1C3=C(C=C(C=C3)OC)C(=NC2CC(=O)O)C4=CC=C(C=C4)Cl
InChI :
InChI=1S/C20H17ClN4O3/c1-11-23-24-20-16(10-18(26)27)22-19(12-3-5-13(21)6-4-12)15-9-14(28-2)7-8-17(15)25(11)20/h3-9,16H,10H2,1-2H3,(H,26,27)/t16-/m0/s1
InChIKey :
VEIZLTSJCDOIBH-INIZCTEOSA-N
Solubility :
DMSO : 7.14 mg/mL (ultrasonic)
Storage : Powder -20°C 3 years; 4°C 2 years; In solvent -80°C 6 months; -20°C 1 month
Synonyms :
Molibresib carboxylic acid; GSK525762A carboxylic acid; PROTAC BRD4-binding moiety 2

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